Diana Passaro from the Francis Crick Institute (London, UK) will talk about bone marrow microenvironment alteration in acute myeloid leukemia in Orsay and Cochin institut early March. Her team is  studying the leukemic microenvironment in the bone marrow of immunodeficient mice  engrafted with patient-derived AML samples by using intravital multiphoton imaging and RNA sequencing techniques. Recently, they bioengineered 3D organoids in mice to model the human bone marrow microenvironment. These humanized tissues constitute a valuable in vivo platform they are currently using to translate their observations to the human normal and malignant bone marrow niche.

She will be at Institut Cochin March 1st, 12h, Room Rosalind Franklin, 2nd floor, 22 rue Méchain 75014, Paris. For registration send an email with your name and your professional address at accueil.u1016@inserm.fr

The day after, March 2, she will talk a the Orsay research center  at 11h30, Amphithéâtre du bâtiment 111, Centre de Recherche d’Orsay. More informations